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Pancreatic Cancer Herbal terapi and fasting effective Indonesia Islami Lampoenk
They report a significant decrease in the levels of the antioxidants, cytosolic superoxide dismutase (Cu/Zn SOD) and glutathione, whereas mitochondrial SOD levels remained unaffected in pancreatic beta-cells (INS-1 cells) exposed to nelfinavir. However, the mitochondrial uncoupling protein (UCP2) levels were up-regulated during nelfinavir induced oxidative stress and directly affected the ATP levels in these cells. A significant decrease in ATP production was also observed which may account for the decrease in glucose stimulated insulin secretion upon nelfinavir treatment.
This study appears in the April 2009 issue of Experimental Biology and Medicine.
Although insulin resistance has been clinically observed in HIV-1 patients receiving HAART regimen, the molecular mechanisms of this metabolic abnormality have not been delineated.
The research team led by Dr. Krishna C. Agrawal, Regents Professor and Chairman included Surabhi Chandra, a graduate student and another faculty member, Dr. Debasis Mondal in the Department of Pharmacology. These investigators successfully tested the hypothesis that nelfinavir induced oxidative stress was responsible for the deleterious effects of the HIV-1 protease inhibitor on insulin production by pancreatic beta-cells and they further investigated the therapeutic strategies to ameliorate the insulin dysregulation at this level. Since the hypoglycemic effects of Nigella sativa oil have been investigated in the past, the investigators postulated that nelfinavir induced oxidative stress may be ameliorated by the administration of the active ingredient of this oil, thymoquinone.
Furthermore, it was envisioned that since thymoquinone shares a structural homology with ubiquinone (mitochondrial component) it is likely that it may act as a mitochondrial antioxidant. Indeed pretreatment of pancreatic beta-cells with thymoquinone caused a reversal of nelfinavir induced deleterious effects. Thymoquinone decreased the production of reactive oxygen species, increased the Cu/Zn SOD and glutathione levels, suppressed the UCP-2 protein levels and restored nelfinavir induced decrease in insulin secretion to normal levels in these cells.
Dr. Agrawal commented, "An important finding of this study is that the dysregulation of insulin production in pancreatic beta-cells is due to generation of reactive oxygen species induced by nelfinavir, an HIV-1 protease inhibitor."
Furthermore, Dr. Agrawal said, "thymoquinone, an antioxidant provided a significant protection to pancreatic beta-cells from the toxic effects of nelfinavir and therefore these findings clearly suggest a potential role for the use of black seed oil or thymoquione as a protective agent against HIV-1 protease inhibitor induced deleterious effects on pancreatic beta-cells." read more
Fasting will break down tumors. For this reason, many have overcome cancer with fasting. Water fasting is a powerful way to fight cancer but it may not be enough. We recommend water fasting combined with days of juice fasting to rebuild the body and supply the nutrients that enable healing.
Cancer fights for the body's resources. The wasting away seen in cancer is from the cancer consuming the glucose in the blood. To battle cancer with fasting the best choice is a combination of water fasting and juice fasting using 2-5 classes of juice per day, including green leafy vegetable like spinach, chard, or parsley to maintain strength and support the body's immune system. This may require 2-3 fast over 14 days long alternating to a diet high in raw foods. Essiac Tea, Jason Winters Herbal Tea are some of the herbal combination proven in fighting cancer.
With juice fasting you can come out a winner in a battle against cancer but you have to move quickly. Buy a juicer and make green vegetable juices from kales spinach, green lettuce, leeks, and lemons. Strain the juice. Drink 1/2 cup every hour. Drink Essiac Tea between the juices. Use an enema daily. Go to your local health store and buy the herbs and supplements that is recommended in the book Prescription for Healing. Ask you friends to pray. When faced with the decision for surgery get alone and pray when you get peace about the decision that is the right one. Do not make decisions out of fear and family pressures. The key to battling cancer with juice fasting is small amount of low-calorie nutrition packed juice. Thus you get maximum scouring. Some persistent forms of cancer may take 40 days of fasting. Move into the fast quickly, it is a race against time especially in pancreatic cancer or any aggressive cancer.
You will most lightly be without hunger throughout the fast. The absence of hunger can last days or weeks making the fast easy to stay on.
You will most lightly be without hunger throughout the fast. The absence of hunger can last days or weeks making the fast easy to stay on.
Fasting tip: Dizziness
You may experience dizziness, if you do get down on one knee and the dizziness will stop immediately. For more on juice and water fasting click on the links provided on the left.
Chemotherapy or RadiationYou may experience dizziness, if you do get down on one knee and the dizziness will stop immediately. For more on juice and water fasting click on the links provided on the left.
If you choose to undergo chemotherapy or radiation, juice fasting or make fresh juice daily and eating a raw food diet will support the body in combating the negative effects of chemotherapy Read More
